Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.30 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tromethamine SCHEMBL28614671 | 0.89 | TP53 (0.55) | TP53MEN1KMT2ALMNAGABRR1 | |
| Lactic Acid SCHEMBL30297156 | 0.83 | TP53 (0.48) | TP53MEN1KMT2ACYP1A2ALDH1A1 | |
| Tromethamine SCHEMBL6704786 | 0.83 | TP53 (0.48) | TP53MEN1KMT2ALMNAGABRR1 | |
| Acetic Acid SCHEMBL28232411 | 0.81 | MEN1 (0.45) | MEN1KMT2ALMNACYP1A2ALDH1A1 | |
| Deanol SCHEMBL10582731 | 0.79 | TP53 (0.55) | TP53CYP1A2ALDH1A1GABRR1SLC7A5 | |
| Lactic Acid SCHEMBL5569780 | 0.79 | TP53 (0.55) | TP53MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL8531420 | 0.78 | MEN1 (0.60) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL45629 | 0.78 | — | — | |
| Lactic Acid SCHEMBL3674426 | 0.77 | TP53 (0.52) | TP53CYP1A2GABRR1OR51E2CHRM1 | |
| Tromethamine SCHEMBL30296964 | 0.77 | MEN1 (0.53) | TP53MEN1KMT2ALMNAGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250090437-A1 | COSMETIC COMPOUNDING AGENT, COSMETIC AND PRODUCTION METHOD THEREOF | MIYOSHI YUSHI KK (JP) | 2025-03-20 | — | — | US | disclosed |
| CN-113423470-B | Cosmetic compounding agent, cosmetic, and method for producing same | 三吉油脂株式会社 | 2024-07-09 | — | — | CN | disclosed |
| US-20220096349-A1 | COSMETIC COMPOUNDING AGENT, COSMETIC AND PRODUCTION METHOD THEREOF | MIYOSHI OIL & FAT CO., LTD. (JP) | 2022-03-31 | — | — | US | disclosed |
| EP-3925671-A1 | COSMETIC INGREDIENT, COSMETIC, AND PRODUCTION METHOD FOR COSMETIC | Miyoshi Oil & Fat Co., Ltd. (JP) | 2021-12-22 | — | — | EP | disclosed |
| CN-113423470-A | Cosmetic compounding agent, cosmetic and method for producing same | 三吉油脂株式会社 | 2021-09-21 | — | — | CN | disclosed |
| WO-2020166678-A1 | COSMETIC INGREDIENT, COSMETIC, AND PRODUCTION METHOD FOR COSMETIC | ミヨシ油脂株式会社 | 2020-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220096349-A1 | COSMETIC COMPOUNDING AGENT, COSMETIC AND PRODUCTION METHOD THEREOF | H1-0, H1-4, H1-2 | CHRM1 732/4885HTR2A 1319/4885HRH1 102/4885 |
| US-20250090437-A1 | COSMETIC COMPOUNDING AGENT, COSMETIC AND PRODUCTION METHOD THEREOF | CUTA, HAT1, NACA | CHRM1 3373/4885HTR2A 1741/4885HRH1 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.