Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15484838 | 0.79 | CPA1 (0.38) | PTGS2ALDH1A1PTGS1 | |
| SCHEMBL30536043 | 0.78 | PTGS2 (0.37) | PTGS2ALDH1A1PTGS1 | |
| SCHEMBL7556173 | 0.75 | CPA1 (0.42) | SMN1; SMN2ALDH1A1CA14 | |
| SCHEMBL14680929 | 0.73 | — | — | |
| SCHEMBL15910174 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1CA14 | |
| SCHEMBL445678 | 0.73 | — | — | |
| SCHEMBL10125303 | 0.73 | — | — | |
| SCHEMBL6354071 | 0.72 | — | — | |
| SCHEMBL13397168 | 0.71 | ALDH1A1 (0.34) | PTGS2SMN1; SMN2ALDH1A1PTGS1KMT2A | |
| SCHEMBL29227567 | 0.71 | ALDH1A1 (0.42) | PTGS2ALDH1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101245-A1 | NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPATHIC PAIN | NICOX S.A. (FR) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011092065-A1 | NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPHATIC PAIN | NICOX S.A. (FR) | 2011-08-04 | — | — | WO | disclosed |