SCHEMBL22348

SCHEMBL22348

OC(Cl)(Cl)C1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2047837 0.67
SCHEMBL8859059 0.67
SCHEMBL8222431 0.65 THRB (0.32)
SCHEMBL8223094 0.65 THRB (0.32)
SCHEMBL12557497 0.65 THRB (0.32)
SCHEMBL7666722 0.64
SCHEMBL262893 0.62 TSHR (0.37)
SCHEMBL818571 0.61
SCHEMBL5623606 0.61
SCHEMBL22804029 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0142769-B1 TETRAHYDROBENZOTRIAZOLES, THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-02 EP claimed
US-4668278-A Benzotriazoles, and their production and use 4-halophenyl-tetrahydrobenzotriazloes as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-26 US claimed
EP-0142769-A2 Tetrahydrobenzotriazoles, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-05-29 EP claimed
EP-2608666-A1 PHENYLAMIDINES HAVING A HIGH FUNGICIDAL ACTIVITY AND USE THEREOF ISAGRO S.p.A. (IT) 2013-07-03 EP disclosed
WO-2012025450-A1 PHENYLAMIDINES HAVING A HIGH FUNGICIDAL ACTIVITY AND USE THEREOF ISAGRO RICERCA S.R.L. (IT) 2012-03-01 WO disclosed
US-6444616-B1 HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 US disclosed
US-6288297-B1 REACTION OF ALDEHYDE WITH TRICHLOROACETIC ACID OR TRIBROMOACETIC ACID IN THE PRESENCE OF BASE CATALYST TO FORM HALOGENATED ALCOHOL, ETHERIFICATION IN THE PRESENCE OF COUPLING CATALYST AND ACID SCAVENGER DUPONT PHARMACEUTICALS COMPANY 2001-09-11 US disclosed
US-6130225-A Substituted p-trifluoromethylphenyluracils BAYER AKTIENGESELLSCHAFT (DE) 2000-10-10 US disclosed
EP-0274066-B1 BENZOTHIAZOLONES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
EP-0142769-B1 TETRAHYDROBENZOTRIAZOLES, THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-02 EP disclosed
US-4740619-A HERBILIDE INTERMEDIATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-04-26 US disclosed
US-4740619-A HERBILIDE INTERMEDIATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-04-26 US disclosed
US-4668278-A Benzotriazoles, and their production and use 4-halophenyl-tetrahydrobenzotriazloes as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-26 US disclosed
US-4668278-A Benzotriazoles, and their production and use 4-halophenyl-tetrahydrobenzotriazloes as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-26 US disclosed
EP-0142769-A2 Tetrahydrobenzotriazoles, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-05-29 EP disclosed
EP-0142769-A2 Tetrahydrobenzotriazoles, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-05-29 EP disclosed