Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458322 | 0.86 | NR1H4 (0.38) | NR1H4 | |
| SCHEMBL22347797 | 0.84 | NR1H4 (0.34) | NR1H4 | |
| SCHEMBL22348688 | 0.83 | NR1H4 (0.45) | NR1H4 | |
| SCHEMBL22348689 | 0.82 | NR1H4 (0.44) | NR1H4 | |
| SCHEMBL22348652 | 0.78 | NR1H4 (0.50) | NR1H4 | |
| SCHEMBL22348708 | 0.75 | NR1H4 (0.59) | NR1H4 | |
| SCHEMBL22353627 | 0.72 | NR1H4 (0.43) | NR1H4 | |
| SCHEMBL29458342 | 0.72 | NR1H4 (0.42) | NR1H4 | |
| SCHEMBL22347965 | 0.71 | GLA (0.43) | NR1H4 | |
| SCHEMBL22348638 | 0.71 | GRK2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924333-A1 | SUBSTITUTED AMIDE COMPOUNDS USEFUL AS FARNESOID X RECEPTOR MODULATORS | Bristol-Myers Squibb Company (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020168149-A1 | SUBSTITUTED AMIDE COMPOUNDS USEFUL AS FARNESOID X RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-20 | — | — | WO | disclosed |