Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.47 |
| ▸ | PTGES | O14684 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | IAPP | P10997 | 3/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060200 | 0.89 | ALOX5 (0.49) | ALOX5PTGESPPARGIAPPCAPN1 | |
| SCHEMBL31256756 | 0.87 | IAPP (0.60) | ALOX5PTGESPPARGIAPPCAPN1 | |
| SCHEMBL2233170 | 0.84 | ALOX5 (0.50) | ALOX5PTGESPPARGIAPPCAPN1 | |
| SCHEMBL2232408 | 0.83 | ALOX5 (0.47) | ALOX5PTGESPPARGIAPPCAPN1 | |
| SCHEMBL13103445 | 0.83 | ALOX5 (0.49) | ALOX5PTGESPPARGIAPPCAPN1 | |
| SCHEMBL3437102 | 0.83 | ALOX5 (0.49) | ALOX5PTGESPPARGIAPPCAPN1 | |
| SCHEMBL3437103 | 0.83 | ALOX5 (0.49) | ALOX5PTGESPPARGIAPPCAPN1 | |
| SCHEMBL16429273 | 0.82 | APP (0.62) | ALOX5PTGESPPARGIAPPCAPN1 | |
| SCHEMBL16429275 | 0.82 | APP (0.62) | ALOX5PTGESPPARGIAPPCAPN1 | |
| SCHEMBL30839919 | 0.82 | APP (0.62) | ALOX5PTGESPPARGIAPPCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |