Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913428 | 0.89 | PDE4D (0.44) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL18022107 | 0.84 | PDE4D (0.42) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL20749914 | 0.83 | TBXA2R (0.60) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL20740218 | 0.83 | TBXA2R (0.60) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL20740219 | 0.83 | TBXA2R (0.60) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL22350173 | 0.83 | PTGFR (0.39) | KDM4EPTGFRTBXA2RPTGER1PTGER3 | |
| SCHEMBL22350175 | 0.83 | PTGFR (0.39) | KDM4EPTGFRTBXA2RPTGER1PTGER3 | |
| SCHEMBL20749941 | 0.81 | PDE4D (0.58) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL10634009 | 0.80 | ALDH1A1 (0.33) | PDE4DALDH1A1 | |
| SCHEMBL11017257 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454227-B1 | SYNTHESIS OF PROSTANOIDS | PATHEON API SERVICES INC (US) | 2020-08-19 | — | — | EP | disclosed |