Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGFR | P43088 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22350151 | 1.00 | PTGER1 (0.49) | PTGER1PTGFRPTGER2SLC18A2SLCO2A1 | |
| SCHEMBL27516839 | 0.99 | PTGER1 (0.48) | PTGER1PTGFRPTGER2SLC18A2SLCO2A1 | |
| SCHEMBL18440461 | 0.82 | SLC18A2 (0.54) | SLC18A2 | |
| SCHEMBL14449247 | 0.79 | PTGFR (0.52) | PTGER1PTGFRPTGER2SLCO2A1LTB4R | |
| SCHEMBL11474308 | 0.79 | SLC18A3 (0.51) | SLC18A2 | |
| SCHEMBL4256995 | 0.78 | LTB4R (0.53) | PTGER1PTGFRPTGER2SLC18A2SLCO2A1 | |
| SCHEMBL31354792 | 0.77 | LTB4R (0.52) | PTGER1PTGFRPTGER2SLC18A2LTB4R | |
| SCHEMBL13568632 | 0.77 | SLC18A3 (0.49) | SLC18A2 | |
| SCHEMBL11724925 | 0.76 | PTGFR (0.55) | PTGER1PTGFRPTGER2SLCO2A1LTB4R | |
| SCHEMBL14626799 | 0.75 | PTGFR (0.51) | PTGER1PTGFRPTGER2SLCO2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454227-B1 | SYNTHESIS OF PROSTANOIDS | PATHEON API SERVICES INC (US) | 2020-08-19 | — | — | EP | disclosed |