Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGFR | P43088 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31354792 | 0.98 | LTB4R (0.52) | LTB4RLTB4R2PTGER2PTGER1PTGFR | |
| SCHEMBL4799370 | 0.80 | MMP2 (0.55) | — | |
| SCHEMBL5446010 | 0.78 | PTGER1 (0.43) | LTB4RLTB4R2PTGER2PTGER1PTGFR | |
| SCHEMBL22350147 | 0.78 | PTGER1 (0.49) | LTB4RLTB4R2PTGER2PTGER1PTGFR | |
| SCHEMBL22350151 | 0.78 | PTGER1 (0.49) | LTB4RLTB4R2PTGER2PTGER1PTGFR | |
| SCHEMBL705394 | 0.78 | CTSS (0.56) | OPRM1OPRD1OPRK1SLC18A2CTSS | |
| SCHEMBL4256993 | 0.77 | MMP12 (0.47) | PTGER2PTGER1PTGFR | |
| SCHEMBL27516839 | 0.77 | PTGER1 (0.48) | LTB4RLTB4R2PTGER2PTGER1PTGFR | |
| SCHEMBL60979 | 0.76 | CTSS (0.54) | EPHX2OPRM1OPRD1OPRK1SLC18A2 | |
| SCHEMBL15655712 | 0.76 | LTB4R (0.46) | LTB4RLTB4R2PTGER2PTGER1PTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666751-A1 | METHOD FOR PREPARING LATANOPROSTENE BUNOD, AND INTERMEDIATE THEREFOR | Yonsung Fine Chemical Co., Ltd. (KR) | 2020-06-17 | — | — | EP | disclosed |
| US-20090035279-A1 | GENETIC VARIANTS ON CHR 15Q24 AS MARKERS FOR USE IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF EXFOLIATION SYNDROME AND GLAUCOMA | DECODE GENETICS EFH (IS) | 2009-02-05 | — | — | US | disclosed |