Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.43 |
| ▸ | FURIN | P09958 | 5/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.42 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25832984 | 0.84 | FURIN (0.35) | SIRT1SMN1; SMN2FURINC3AR1SIRT5 | |
| SCHEMBL24140485 | 0.83 | SIRT2 (0.45) | SIRT1SIRT2FURINSIRT3SIRT5 | |
| SCHEMBL22266602 | 0.81 | ALB (0.43) | SIRT1SMN1; SMN2FURINSIRT5 | |
| SCHEMBL22690704 | 0.80 | FURIN (0.45) | SIRT1SMN1; SMN2SIRT2FURINSIRT3 | |
| SCHEMBL17133812 | 0.80 | FURIN (0.45) | SIRT1SMN1; SMN2SIRT2FURINSIRT3 | |
| SCHEMBL17133811 | 0.80 | FURIN (0.45) | SIRT1SMN1; SMN2SIRT2FURINSIRT3 | |
| SCHEMBL22690700 | 0.80 | FURIN (0.45) | SIRT1SMN1; SMN2SIRT2FURINSIRT3 | |
| SCHEMBL23760646 | 0.80 | SIRT5 (0.36) | SIRT1SMN1; SMN2FURINC3AR1SIRT5 | |
| SCHEMBL26431147 | 0.80 | HTT (0.46) | SIRT1SMN1; SMN2FURINSIRT5 | |
| SCHEMBL24864483 | 0.79 | FURIN (0.43) | SMN1; SMN2FURINSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165600-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |