Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 9/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29342070 | 0.90 | FURIN (0.42) | FURINHTT | |
| SCHEMBL29339853 | 0.90 | FURIN (0.43) | FURINSIRT5SMN1; SMN2HTTBACE1 | |
| SCHEMBL29342071 | 0.90 | FURIN (0.43) | FURINSIRT5BACE1 | |
| SCHEMBL31559077 | 0.86 | SIRT5 (0.57) | SIRT5 | |
| SCHEMBL17133811 | 0.86 | FURIN (0.45) | FURINSMN1; SMN2HTT | |
| SCHEMBL17133812 | 0.86 | FURIN (0.45) | FURINSMN1; SMN2HTT | |
| SCHEMBL29342072 | 0.86 | FURIN (0.45) | FURINSMN1; SMN2HTT | |
| SCHEMBL24864662 | 0.86 | FURIN (0.44) | FURINSIRT5SMN1; SMN2HTTBACE1 | |
| SCHEMBL24864481 | 0.85 | FURIN (0.43) | FURINSMN1; SMN2HTTBACE1 | |
| SCHEMBL29345954 | 0.85 | FURIN (0.44) | FURINSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |