Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22404257 | 0.83 | RXRA (0.33) | RXRAGRIN1GRIN2BBRD4NOTUM | |
| SCHEMBL22753520 | 0.83 | RXRA (0.33) | RXRAGRIN1GRIN2BBRD4NOTUM | |
| SCHEMBL21955621 | 0.80 | RXRA (0.39) | RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL20282459 | 0.75 | RXRA (0.48) | RXRAGRIN1GRIN2B | |
| SCHEMBL20282458 | 0.75 | RXRA (0.48) | RXRAGRIN1GRIN2B | |
| SCHEMBL25667120 | 0.74 | RXRA (0.45) | RXRAGRIN1GRIN2BNOTUMLRRK2 | |
| SCHEMBL23008630 | 0.74 | CYP1B1 (0.37) | RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL24754348 | 0.74 | RXRA (0.55) | RXRAGRIN1GRIN2B | |
| SCHEMBL25847222 | 0.74 | RXRA (0.42) | RXRAGRIN1GRIN2B | |
| SCHEMBL26178710 | 0.74 | HMGB1 (0.40) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165600-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |