Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 17/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 17/20 | 0.55 |
| ▸ | ESRRA | P11474 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820296 | 0.87 | RXRA (0.58) | RXRAGRIN1GRIN2BESRRAFLT1 | |
| SCHEMBL25897473 | 0.82 | BCHE (0.48) | RXRAGRIN1GRIN2B | |
| SCHEMBL16775726 | 0.80 | RXRA (0.70) | RXRAGRIN1GRIN2BESRRATRPV1 | |
| SCHEMBL25824836 | 0.78 | RXRA (0.58) | RXRAGRIN1GRIN2BESRRAFLT1 | |
| SCHEMBL20282459 | 0.76 | RXRA (0.48) | RXRAGRIN1GRIN2B | |
| SCHEMBL19365355 | 0.76 | RXRA (0.67) | RXRAGRIN1GRIN2BESRRATRPV1 | |
| SCHEMBL19211451 | 0.76 | RXRA (0.67) | RXRAGRIN1GRIN2B | |
| SCHEMBL20282458 | 0.76 | RXRA (0.48) | RXRAGRIN1GRIN2B | |
| SCHEMBL25847222 | 0.75 | RXRA (0.42) | RXRAGRIN1GRIN2B | |
| SCHEMBL22352192 | 0.74 | RXRA (0.33) | RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266248-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2022-12-22 | — | — | WO | disclosed |