SCHEMBL22352404

SCHEMBL22352404

c1ccc(-c2ccc(N(c3ccccc3)c3ccc4c5ccc6c7ccccc7n(-c7ccccc7)c6c5n(-c5ccccc5)c4c3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.45
▸ L3MBTL1 Q9Y468 3/20 0.45
▸ ATM Q13315 1/20 0.45
▸ KMT2A Q03164 2/20 0.36
▸ IL1R1 P14778 1/20 0.36
▸ ALDH1A1 P00352 5/20 0.35
▸ MAPT P10636 3/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ MAPK8 P45983 2/20 0.33
▸ TSPO P30536 1/20 0.33
▸ HDAC4 P56524 1/20 0.33
▸ KDR P35968 1/20 0.33
▸ MAPK9 P45984 1/20 0.33
▸ REN P00797 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ AVPR1A P37288 1/20 0.31
▸ CYP1A2 P05177 2/20 0.31
▸ CYP3A4 P08684 2/20 0.31
▸ CYP2C9 P11712 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22352551 0.93 L3MBTL1 (0.44) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL21128757 0.93 KDM4E (0.53) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL11922030 0.93 KDM4E (0.53) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL11922042 0.93 KDM4E (0.53) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL31670 0.93 L3MBTL1 (0.49) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL24090446 0.93 KDM4E (0.53) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL16976362 0.93 KDM4E (0.53) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL11922043 0.92 KDM4E (0.55) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL11922019 0.92 KDM4E (0.55) KDM4EL3MBTL1ATMKMT2AIL1R1
SCHEMBL17932813 0.92 KDM4E (0.55) KDM4EL3MBTL1ATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029112-B2 Composition for optoelectronic device and organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2024-07-02 — — US disclosed
US-12029112-B2 Composition for optoelectronic device and organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2024-07-02 — — US disclosed
WO-2022211594-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2022-10-06 — — WO disclosed
US-20220069240-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-03-03 — — US disclosed
US-20210009616-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD (KR) 2021-01-14 — — US disclosed
US-20200266357-A1 COMPOSITION FOR OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-08-20 — — US disclosed
US-20200266358-A1 COMPOSITION FOR OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-08-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200266358-A1 COMPOSITION FOR OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 KDM4E 4632/4885L3MBTL1 4844/4885ATM 3757/4885
US-20210009616-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SLC39A14, ORC3, TIMM13 KDM4E 3352/4885L3MBTL1 431/4885ATM 2386/4885
US-20200266357-A1 COMPOSITION FOR OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 KDM4E 4551/4885L3MBTL1 4842/4885ATM 3601/4885
US-12029112-B2 Composition for optoelectronic device and organic optoelectronic device and display device OR10J3, OCIAD2, OCIAD1 KDM4E 4632/4885L3MBTL1 4844/4885ATM 3757/4885
US-20220069240-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ORC3, LAGE3, ERCC1 KDM4E 3733/4885L3MBTL1 310/4885ATM 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback