SCHEMBL22352467

SCHEMBL22352467

c1ccc(-c2nc(-c3ccc4c(c3)sc3ccc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)cc34)nc(-c3cccc4sc5ccccc5c34)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTGER4 P35408 1/20 0.32
PIM3 Q86V86 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23947897 1.00 KDM4E (0.33) KDM4EATML3MBTL1PTGER4PIM3
SCHEMBL26169132 0.98 KDM4E (0.35) KDM4EATML3MBTL1PTGER4
SCHEMBL22352294 0.98 KDM4E (0.35) KDM4EATML3MBTL1PTGER4
SCHEMBL26169128 0.97 KDM4E (0.34) KDM4EATML3MBTL1PTGER4PIM3
SCHEMBL23947428 0.96 KDM4E (0.33) KDM4EATML3MBTL1PIM3
SCHEMBL23947857 0.96 KDM4E (0.33) KDM4EATML3MBTL1PIM3
SCHEMBL23947898 0.96 KDM4E (0.36) KDM4EATML3MBTL1PTGER4PIM3
SCHEMBL26168667 0.96 KDM4E (0.36) KDM4EATML3MBTL1PTGER4
SCHEMBL23947807 0.95 KDM4E (0.34) KDM4EATML3MBTL1PTGER4
SCHEMBL17252846 0.95 KDM4E (0.35) KDM4EATML3MBTL1PTGER4PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873297-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11873297-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11515484-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2022-11-29 US disclosed
US-20210323948-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-10-21 US disclosed
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME HEESUNG MATERIAL LTD. (KR) 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11515484-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 KDM4E 2341/4885ATM 2995/4885L3MBTL1 1142/4885
US-20210323948-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CCNL2, UBE2L3, OPRL1 KDM4E 3842/4885ATM 2218/4885L3MBTL1 94/4885
US-11873297-B2 Compound and organic light emitting device comprising the same CCNL2, UBE2L3, ARL1 KDM4E 3695/4885ATM 2154/4885L3MBTL1 83/4885
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 KDM4E 2341/4885ATM 2995/4885L3MBTL1 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.