Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22352984 | 0.88 | ALDH1A1 (0.59) | ALDH1A1ELOVL1RAB9ALMNANPC1 | |
| SCHEMBL19576953 | 0.88 | ALDH1A1 (0.53) | ALDH1A1ELOVL1RAB9ALMNANPC1 | |
| SCHEMBL19576990 | 0.88 | CA12 (0.52) | ALDH1A1ELOVL1RAB9ALMNANPC1 | |
| SCHEMBL19577012 | 0.88 | KMT2A (0.47) | ALDH1A1RAB9ALMNANPC1KMT2A | |
| SCHEMBL19576836 | 0.88 | KCNJ5 (0.55) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19576846 | 0.85 | ALDH1A1 (0.50) | ALDH1A1ELOVL1RAB9ALMNANPC1 | |
| SCHEMBL22353189 | 0.85 | ALDH1A1 (0.50) | ALDH1A1ELOVL1RAB9ALMNANPC1 | |
| SCHEMBL19576983 | 0.84 | SMN1; SMN2 (0.43) | ALDH1A1RAB9ALMNASMN1; SMN2ITGB1 | |
| SCHEMBL19576985 | 0.81 | P2RX7 (0.48) | LMNA | |
| SCHEMBL19576877 | 0.80 | RECQL (0.52) | ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458443-B1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma AG (DE) | 2020-08-19 | — | — | EP | disclosed |