Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25587750 | 0.91 | KDM4E (0.34) | KDM4ETDP1TSHR | |
| SCHEMBL344219 | 0.89 | TDP1 (0.36) | KDM4ETDP1TSHR | |
| SCHEMBL1144943 | 0.89 | TDP1 (0.40) | KDM4ETDP1TSHR | |
| SCHEMBL20994688 | 0.89 | TDP1 (0.40) | KDM4ETDP1TSHR | |
| SCHEMBL20216922 | 0.89 | TDP1 (0.40) | KDM4ETDP1TSHR | |
| SCHEMBL131477 | 0.89 | TDP1 (0.40) | KDM4ETDP1TSHR | |
| SCHEMBL6381056 | 0.89 | KDM4E (0.35) | KDM4ETDP1TSHR | |
| SCHEMBL19699299 | 0.88 | MAPT (0.42) | KDM4ETSHR | |
| SCHEMBL25489387 | 0.86 | TDP1 (0.35) | KDM4ETDP1TSHR | |
| SCHEMBL4749725 | 0.86 | KDM4E (0.35) | KDM4ETDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159581-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | SYNOVO GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20200262857-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | SYNOVO GMBH (DE) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159581-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | CTSA, ALOX15, ALOX5 | KDM4E 3648/4885TDP1 3576/4885TSHR 4450/4885 |
| US-20200262857-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | CTSA, ALOX15, ALOX5 | KDM4E 3648/4885TDP1 3576/4885TSHR 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.