Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.80 |
| ▸ | WDR77 | Q9BQA1 | 17/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15833707 | 0.89 | PRMT5 (1.00) | PRMT5WDR77LMNAHTTSMN1; SMN2 | |
| SCHEMBL30019323 | 0.89 | CARM1 (0.74) | PRMT5WDR77LMNAHTT | |
| SCHEMBL15943835 | 0.88 | PRMT5 (1.00) | PRMT5WDR77LMNAHTTSMN1; SMN2 | |
| SCHEMBL15833619 | 0.87 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL18776486 | 0.87 | PRMT5 (1.00) | PRMT5WDR77SMN1; SMN2 | |
| SCHEMBL2257001 | 0.85 | PRMT5 (0.65) | PRMT5WDR77LMNAHTTSMN1; SMN2 | |
| SCHEMBL15833547 | 0.85 | PRMT5 (1.00) | PRMT5WDR77LMNAHTTSMN1; SMN2 | |
| SCHEMBL15943979 | 0.85 | PRMT5 (0.82) | PRMT5WDR77SMN1; SMN2 | |
| SCHEMBL15833542 | 0.85 | PRMT5 (1.00) | PRMT5WDR77LMNAHTTSMN1; SMN2 | |
| SCHEMBL15943831 | 0.85 | PRMT5 (1.00) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159581-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | SYNOVO GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230159581-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | SYNOVO GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230131943-A1 | ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS | BURNET MICHEAL W (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230131943-A1 | ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS | BURNET MICHEAL W (DE) | 2023-04-27 | — | — | US | disclosed |
| WO-2021195126-A1 | ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS | BURNET MICHAEL W (DE) | 2021-09-30 | — | — | WO | disclosed |
| US-20200262857-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | SYNOVO GMBH (DE) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131943-A1 | ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS | CTSA, GAA, SLC7A5 | PRMT5 4082/4885WDR77 2298/4885LMNA 4327/4885 |
| US-20230159581-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | CTSA, ALOX15, ALOX5 | PRMT5 4712/4885WDR77 3872/4885LMNA 4335/4885 |
| US-20200262857-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | CTSA, ALOX15, ALOX5 | PRMT5 4712/4885WDR77 3872/4885LMNA 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.