SCHEMBL22355338

SCHEMBL22355338

CC(C)(O)C(=O)c1ccc2c(c1)C(C)(C)c1cc(C(=O)C(C)(C)O)ccc1-2

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 16/20 0.39
▸ NPC1 O15118 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ RXRA P19793 2/20 0.32
▸ RXRB P28702 2/20 0.32
▸ RARB P10826 1/20 0.32
▸ RARG P13631 1/20 0.32
▸ RXRG P48443 1/20 0.32
▸ ALK Q9UM73 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22355349 0.92 PDK2 (0.47) PDK2
SCHEMBL22989413 0.89 KDM4E (0.41) PDK2
SCHEMBL14073423 0.84 PDK2 (0.38) PDK2NPC1MAPTRAB9A
SCHEMBL17559567 0.81 CTNNB1 (0.34) RXRARXRBRARBRARGRXRG
SCHEMBL22355385 0.81 PDK2 (0.37) PDK2NPC1MAPTRAB9A
SCHEMBL22745171 0.79 PDK2 (0.35) PDK2
SCHEMBL22355343 0.79 PDK2 (0.35) PDK2NPC1MAPTRAB9AALK
SCHEMBL21439836 0.77 RARB (0.46) PDK2MAPTRXRARXRBRARB
SCHEMBL29371850 0.77 RARB (0.46) PDK2MAPTRXRARXRBRARB
SCHEMBL15040998 0.77 MAPT (0.57) PDK2NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11054743-B2 Fluorene polyfunctional photoinitiator and preparation and use thereof, and photosensitive resin composition containing fluorene photoinitiator and use thereof CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2021-07-06 — — US disclosed
EP-3392232-B1 FLUORENE MULTIFUNCTIONAL PHOTOINITIATOR AND PREPARATION AND USE THEREOF, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING FLUORENE PHOTOINITIATOR AND USE THEREOF CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-02-17 — — EP disclosed
US-20200264508-A1 FLUORENE POLYFUNCTIONAL PHOTOINITIATOR AND PREPARATION AND USE THEREOF, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING FLUORENE PHOTOINITIATOR AND USE THEREOF CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2020-08-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11054743-B2 Fluorene polyfunctional photoinitiator and preparation and use thereof, and photosensitive resin composition containing fluorene photoinitiator and use thereof RARA, RARG, PFAS PDK2 3326/4885NPC1 4697/4885MAPT 1621/4885
US-20200264508-A1 FLUORENE POLYFUNCTIONAL PHOTOINITIATOR AND PREPARATION AND USE THEREOF, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING FLUORENE PHOTOINITIATOR AND USE THEREOF RARA, RARG, PFAS PDK2 3326/4885NPC1 4697/4885MAPT 1621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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