Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456470 | 0.81 | TP53 (0.34) | ALDH1A1TP53SMN1; SMN2HPGD | |
| SCHEMBL10691257 | 0.74 | — | — | |
| SCHEMBL512925 | 0.73 | ALDH1A1 (0.36) | USP7CYP1A2MEN1KMT2ASLC6A3 | |
| SCHEMBL509857 | 0.71 | AHR (0.45) | AHRCYP1A2MEN1KMT2ASLC6A3 | |
| SCHEMBL455996 | 0.70 | CYP2A6 (0.38) | CYP1A2TP53 | |
| SCHEMBL456752 | 0.70 | CYP2A6 (0.38) | CYP1A2TP53 | |
| SCHEMBL454988 | 0.70 | — | — | |
| SCHEMBL456111 | 0.69 | CYP1A2 (0.38) | AHRCYP1A2MEN1KMT2ASLC6A3 | |
| SCHEMBL455613 | 0.67 | — | — | |
| SCHEMBL468085 | 0.67 | GABRA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534133-A2 | BIPHENYL SUBSTITUTED CYCLICAL KETO-ENOLS | Bayer Intellectual Property GmbH (DE) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011098440-A2 | BIPHENYL SUBSTITUTED CYCLICAL KETO-ENOLS | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | WO | disclosed |