SCHEMBL223560

SCHEMBL223560

Clc1cccc(N(c2ccccc2)c2ccc(C3C=CC(c4ccccc4)(N(c4ccccc4)c4cccc(Cl)c4)C=C3)cc2)c1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.31
HSD11B1 P28845 1/20 0.30
MAPT P10636 2/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4213708 0.88 ALDH1A1 (0.35) MAPTALDH1A1
SCHEMBL8862830 0.87
SCHEMBL19125480 0.83 KDM4E (0.32) MAPTALDH1A1
SCHEMBL1323554 0.79
SCHEMBL19125938 0.79
SCHEMBL9163093 0.78 MAPT (0.35) MAPT
SCHEMBL2348824 0.78
SCHEMBL2678828 0.76 CYP1A2 (0.33) MAPT
SCHEMBL8083540 0.76 S1PR1 (0.36)
SCHEMBL1042269 0.74 SIGMAR1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3309618-A1 POLYCARBONATE CONTAINING PHOTOCONDUCTORS Xerox Corporation (US) 2018-04-18 EP claimed
US-9851647-B1 Polycarbonate containing photoconductors XEROX CORPORATION (US) 2017-12-26 US claimed
US-20150261105-A1 BIPHENYL POLYCARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-09-17 US claimed
US-9128392-B2 Polyarylatecarbonate containing photoconductors XEROX CORPORATION (US) 2015-09-08 US claimed
US-9069268-B2 Polyarylatecarbonate fluoropolymer containing photoconductors XEROX CORPORATION (US) 2015-06-30 US claimed
US-20150147690-A1 POLYARYLATECARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-05-28 US claimed
US-20150079511-A1 POLYARYLATECARBONATE FLUOROPOLYMER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-03-19 US claimed
US-20140356772-A1 TERPENE POLYCARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2014-12-04 US claimed
US-8815481-B2 Imaging member with fluorosulfonamide-containing overcoat layer XEROX CORPORATION (US) 2014-08-26 US claimed
US-8785091-B1 Polyarylatecarbonate containing photoconductors XEROX CORPORATION (US) 2014-07-22 US claimed
US-7981578-B2 Additive containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-7972756-B2 Ketal containing photoconductors XEROX CORPORATION (US) 2011-07-05 US claimed
US-7968262-B2 Bis(enylaryl)arylamine containing photoconductors XEROX CORPORATION (US) 2011-06-28 US claimed
US-7968263-B2 Amine phosphate containing photogenerating layer photoconductors XEROX CORPORATION (US) 2011-06-28 US claimed
US-20110151365-A1 POLYALKYLENE GLYCOL BENZOATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-06-23 US claimed
US-7960079-B2 Phenazine containing photoconductors XEROX CORPORATION (US) 2011-06-14 US claimed
US-7960080-B2 Oxadiazole containing photoconductors XEROX CORPORATION (US) 2011-06-14 US claimed
US-7951514-B2 Polymer anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2011-05-31 US claimed
US-7932006-B2 Photoconductors XEROX CORPORATION (US) 2011-04-26 US claimed
US-7678517-B2 Single layered photoconductors XEROX CORPORATION (US) 2010-03-16 US claimed