SCHEMBL22356177

SCHEMBL22356177

NCc1ccc(OP(=O)(O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.54
ST14 Q9Y5Y6 3/20 0.52
BLM P54132 1/20 0.52
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
INPPL1 O15357 4/20 0.48
INPP5A Q14642 3/20 0.48
CYP2C19 P33261 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ABAT P80404 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
NCOR2 Q9Y618 1/20 0.42
ANPEP P15144 1/20 0.42
ERAP2 Q6P179 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
INPP5B P32019 1/20 0.41
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27339665 0.98 SRC (0.52) SRCST14BLMCA1CA2
SCHEMBL28106181 0.85 ST14 (0.46) SRCST14BLMCA1CA2
SCHEMBL28031670 0.84 CYP2C19 (0.68) ST14BLMCYP2C19SMN1; SMN2ABAT
SCHEMBL6431657 0.84 TAAR1 (0.52) SRCBLMCA1CA2INPPL1
SCHEMBL329313 0.82 SRC (0.75) SRCBLMCA1CA2INPPL1
SCHEMBL27826220 0.81 SRC (0.53) SRCST14INPPL1INPP5AANPEP
SCHEMBL27938230 0.81 SRC (0.52) SRCST14CYP2C19SMN1; SMN2ANPEP
SCHEMBL4957575 0.81 SRC (0.56) SRCBLMCA1CA2INPPL1
SCHEMBL3123300 0.80 SLC6A4 (0.58) BLMANPEP
SCHEMBL21807707 0.80 SLC6A4 (0.58) BLMANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103146152-A Flame retardant copolyether ester composition and product comprising same DU PONT 2013-06-12 CN claimed
CN-103146153-A Flame-retardant copolyether ester composition and product comprising the flame-retardant copolyether ester composition DU PONT 2013-06-12 CN claimed
US-11040048-B2 Medicament for treating influenza characterized by combining a Cap-dependent endonuclease inhibitor and an anti-influenza drug SHIONOGI & CO., LTD. (JP) 2021-06-22 US disclosed
US-20200261481-A1 A MEDICAMENT FOR TREATING INFLUENZA CHARACTERIZED BY COMBINING A CAP-DEPENDENT ENDONUCLEASE INHIBITOR AND AN ANTI-INFLUENZA DRUG SHIONOGI & CO., LTD. (JP) 2020-08-20 US disclosed
CN-107107049-A Selective hydrogenation catalyst and its preparation and application 切弗朗菲利浦化学公司 2017-08-29 CN disclosed
CN-102341175-B Selective hydrogenation catalyst and preparation and application thereof Chevron Phillips Chemical Co.,L.P. (US) 2016-11-30 CN disclosed
CN-103635497-A Method for polymerizing resin casting for use as epoxy acrylic optical lens and resin composition containing internal releasing agent for use in epoxy acrylic optical lens KOC SOLUTION CO LTD 2014-03-12 CN disclosed
CN-103635520-A Resin composition and molded article FUJIFILM CORP 2014-03-12 CN disclosed
CN-103146152-A Flame retardant copolyether ester composition and product comprising same DU PONT 2013-06-12 CN disclosed
CN-103146153-A Flame-retardant copolyether ester composition and product comprising the flame-retardant copolyether ester composition DU PONT 2013-06-12 CN disclosed
CN-102341175-A Selective hydrogenation catalyst and methods of making and using same CHEVRON PHILLIPS CHEMICAL CO 2012-02-01 CN disclosed
CN-100384917-C Electrically conductive thermoplastic polymer composition DOW GLOBAL TECHNOLOGIES INC (US) 2008-04-30 CN disclosed
CN-100335511-C Vinyl homopolymer or method for producing vinyl and C3-C20 alpha-olefine randompolymer MITSUI CHEMICALS INC (JP) 2007-09-05 CN disclosed
CN-1897810-A Corrosion inhibitors for aqueous pesticide formulations SYNGENTA PARTICIPATIONS AG (CH) 2007-01-17 CN disclosed
CN-1781954-A Vinyl homopolymer or method for producing vinyl and c3-c20 alpha-olefine randompolymer MITSUI CHEMICALS INC (JP) 2006-06-07 CN disclosed
CN-1761706-A Electrically conductive thermoplastic polymer composition DOW GLOBAL TECHNOLOGIES INC (US) 2006-04-19 CN disclosed
CN-1748001-A Halogen free ignition resistant thermoplastic resin compositions DOW GLOBAL TECHNOLOGIES INC (US) 2006-03-15 CN disclosed
CN-1229399-C Ethylene polymer, process for producing the same, and molded article using the same MITSUI CHEMICALS INC (JP) 2005-11-30 CN disclosed
CN-1659217-A Halogen-free flame-retardant thermoplastic resin composition DOW GLOBAL TECHNOLOGIES INC (US) 2005-08-24 CN disclosed
CN-1386768-A Ethylene polymer, process for producing the same, and molded article using the same MITSUI CHEMICALS INC (JP) 2002-12-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200261481-A1 A MEDICAMENT FOR TREATING INFLUENZA CHARACTERIZED BY COMBINING A CAP-DEPENDENT ENDONUCLEASE INHIBITOR AND AN ANTI-INFLUENZA DRUG RNASEH1, RNASEL, RNPEP SRC 3543/4885ST14 2320/4885BLM 3040/4885
US-11040048-B2 Medicament for treating influenza characterized by combining a Cap-dependent endonuclease inhibitor and an anti-influenza drug RNASEH1, RNPEP, RNASEL SRC 3348/4885ST14 2512/4885BLM 3011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.