SCHEMBL22356455

SCHEMBL22356455

C=CC(=O)Oc1cccc(Nc2nc(Nc3cccc(O)c3)nc(Nc3cccc(O)c3)n2)c1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SYK P43405 12/20 0.46
EGFR P00533 2/20 0.44
ITK Q08881 1/20 0.43
RHOA P61586 1/20 0.43
KMT2A Q03164 1/20 0.41
KCNH3 Q9ULD8 1/20 0.41
APP P05067 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22356441 1.00 SYK (0.46) SYKEGFRITKRHOAKMT2A
SCHEMBL22356445 0.96 RHOA (0.49) SYKEGFRITKRHOAKMT2A
SCHEMBL22356453 0.93 EGFR (0.48) EGFRITKRHOAKCNH3
SCHEMBL22356444 0.89 RHOA (0.55) EGFRITKRHOAKMT2AKCNH3
SCHEMBL22356451 0.89 RHOA (0.55) EGFRITKRHOAKMT2AKCNH3
SCHEMBL22356392 0.82 RHOA (0.49) EGFRITKRHOA
SCHEMBL22356457 0.82 SYK (0.47) SYKEGFRITKRHOAKCNH3
SCHEMBL22356460 0.82 SYK (0.47) SYKEGFRITKRHOAKCNH3
SCHEMBL24497065 0.81 IGF1R (0.52) EGFRITK
SCHEMBL22356433 0.80 RHOA (0.54) EGFRITKRHOAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TREEEL CO., LTD (KR) 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200262798-A1 NOVEL TRIAZINE DERIVATIVE AND PHOTOSENSITIVE COMPOSITION COMPRISING SAME TYR, CRY2, CRY1 SYK 1816/4885EGFR 2575/4885ITK 1348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.