Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.38 |
| ▸ | CDC25B | P30305 | 6/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.38 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13582347 | 0.88 | PTPN1 (0.43) | PTPN2PTPN1CDC25BPTPN6POLB | |
| SCHEMBL13582345 | 0.88 | PTPN1 (0.43) | PTPN2PTPN1CDC25BPTPN6POLB | |
| SCHEMBL2231788 | 0.84 | APP (0.38) | APPMAPTMAPK1 | |
| SCHEMBL2232047 | 0.84 | APP (0.47) | ALOX5APP | |
| SCHEMBL2232050 | 0.84 | APP (0.47) | ALOX5APP | |
| SCHEMBL2235847 | 0.83 | ALOX5 (0.41) | ALOX5POLBMAPTMAPK1 | |
| SCHEMBL2234601 | 0.81 | CYP4F2 (0.42) | PTPN2PTPN1CDC25BPTPN6POLB | |
| SCHEMBL2234609 | 0.81 | CYP4F2 (0.42) | PTPN2PTPN1CDC25BPTPN6POLB | |
| SCHEMBL13583139 | 0.81 | APP (0.43) | ALOX5APPMAPTMEN1KMT2A | |
| SCHEMBL13583137 | 0.81 | APP (0.43) | ALOX5APPMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |