Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.41 |
| ▸ | PPARG | P37231 | 10/20 | 0.41 |
| ▸ | PTGES | O14684 | 7/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 12/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231793 | 0.84 | PPARG (0.48) | ALOX5PPARGPTGESPSEN1 | |
| SCHEMBL2235842 | 0.84 | TDP1 (0.37) | ALOX5PPARGPTGESPSEN1POLB | |
| SCHEMBL2232581 | 0.83 | ALOX5 (0.42) | ALOX5PPARGPTGESPSEN1 | |
| SCHEMBL2235837 | 0.83 | ALOX5 (0.42) | ALOX5POLBMAPTMAPK1 | |
| SCHEMBL13582345 | 0.83 | PTPN1 (0.43) | POLBMAPTMAPK1 | |
| SCHEMBL13582347 | 0.83 | PTPN1 (0.43) | POLBMAPTMAPK1 | |
| SCHEMBL13582401 | 0.79 | MAOB (0.43) | MAPT | |
| SCHEMBL13582395 | 0.79 | MAOB (0.43) | MAPT | |
| SCHEMBL2235546 | 0.77 | ALOX5 (0.46) | ALOX5PPARGPTGESPSEN1 | |
| SCHEMBL2234601 | 0.77 | CYP4F2 (0.42) | POLBMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |