Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601154 | 0.93 | — | — | |
| SCHEMBL2139712 | 0.87 | TSHR (0.50) | ALDH1A1TSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL5721434 | 0.87 | TSHR (0.50) | ALDH1A1TSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL2136844 | 0.87 | TSHR (0.50) | ALDH1A1TSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL2746089 | 0.87 | TSHR (0.50) | ALDH1A1TSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL2059697 | 0.87 | TSHR (0.50) | ALDH1A1TSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL5721317 | 0.87 | TSHR (0.50) | ALDH1A1TSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL31296577 | 0.87 | TSHR (0.50) | ALDH1A1TSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL2136691 | 0.87 | TSHR (0.50) | ALDH1A1TSHRCHRM2CHRM4CHRM5 | |
| Ammonia Solution, Strong SCHEMBL322522 | 0.85 | LMNA (0.48) | ALDH1A1TSHRCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020167518-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2020-08-20 | — | — | WO | disclosed |
| CN-102197023-B | Compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC. (US) | 2015-12-16 | — | — | CN | disclosed |