SCHEMBL4601154

SCHEMBL4601154

COCCCOC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22358906 0.93 ALDH1A1 (0.52)
SCHEMBL4696456 0.87 TSHR (0.42)
SCHEMBL2745809 0.87 LMNA (0.52)
SCHEMBL499368 0.84
Ammonia Solution, Strong SCHEMBL10897945 0.84 LMNA (0.50)
Ammonia Solution, Strong SCHEMBL27654016 0.82
SCHEMBL2746597 0.81 TSHR (0.52)
SCHEMBL4886112 0.80 ALDH1A1 (0.58)
SCHEMBL654465 0.79 ALDH1A1 (0.46)
SCHEMBL4755803 0.79 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024134516-A1 NOVEL COMPOUND AS RON INHIBITOR 주식회사 엘지화학 2024-06-27 WO disclosed
US-20240140957-A1 BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF BEONE MEDICINES I GMBH (CH) 2024-05-02 US disclosed
WO-2022148422-A1 BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF BEIGENE, LTD. (KY) 2022-07-14 WO disclosed
US-11040048-B2 Medicament for treating influenza characterized by combining a Cap-dependent endonuclease inhibitor and an anti-influenza drug SHIONOGI & CO., LTD. (JP) 2021-06-22 US disclosed
EP-3681330-B1 ARTICLES COMPRISING COATED FIBERS AND METHODS OF MAKING COATED FIBERS AND ARTICLES NIKE INNOVATE CV (US) 2020-12-23 EP disclosed
US-20200261481-A1 A MEDICAMENT FOR TREATING INFLUENZA CHARACTERIZED BY COMBINING A CAP-DEPENDENT ENDONUCLEASE INHIBITOR AND AN ANTI-INFLUENZA DRUG SHIONOGI & CO., LTD. (JP) 2020-08-20 US disclosed
WO-2008139941-A1 SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-20 WO disclosed
EP-1912645-A2 THERAPEUTIC AGENT FOR DIABETES Takeda Pharmaceutical Company Limited (JP) 2008-04-23 EP disclosed
WO-2007018314-A2 THERAPEUTIC AGENT FOR DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-02-15 WO disclosed
EP-0925318-B1 CARBAMATE FUNCTIONAL POLYMERS AND COMPOSITIONS CONTAINING SAME PPG IND OHIO INC (US) 2004-07-28 EP disclosed
EP-0925318-A1 CARBAMATE FUNCTIONAL POLYMERS AND COMPOSITIONS CONTAINING SAME PPG INDUSTRIES, INC. (US) 1999-06-30 EP disclosed
US-5759694-A Carbamate functional polymers and oligomers and coating compositions containing same PPG INDUSTRIES, INC. (US) 1998-06-02 US disclosed
WO-1998010006-A1 CARBAMATE FUNCTIONAL POLYMERS AND COMPOSITIONS CONTAINING SAME PPG INDUSTRIES, INC. (US) 1998-03-12 WO disclosed
CN-1138327-A Etherified alkyl or arylcarbamoylmethylated aminotriazines and curable compositions containing same PPG INDUSTRIES INC (US) 1996-12-18 CN disclosed
EP-0730585-A1 ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1996-09-11 EP disclosed
US-5545696-A FILM FORMERS IN COATINGS PPG INDUSTRIES, INC. (US) 1996-08-13 US disclosed
US-5536835-A Etherified alkyl or arylcarbamylmethylated aminotriazines and curable compositions containing the same PPG INDUSTRIES, INC. (US) 1996-07-16 US disclosed
US-5462992-A Curable coatings PPG INDUSTRIES, INC. (US) 1995-10-31 US disclosed
WO-1995014677-A1 ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1995-06-01 WO disclosed