Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.40 |
| ▸ | IL6 | P05231 | 5/20 | 0.40 |
| ▸ | BCHE | P06276 | 8/20 | 0.40 |
| ▸ | ACHE | P22303 | 8/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659945 | 1.00 | TLR7 (0.40) | TLR7IL6BCHEACHECACNA1F | |
| SCHEMBL29034576 | 0.89 | TLR7 (0.54) | TLR7IL6 | |
| SCHEMBL26354824 | 0.89 | TLR7 (0.54) | TLR7IL6 | |
| SCHEMBL29034537 | 0.89 | TLR7 (0.39) | TLR7IL6 | |
| SCHEMBL29475724 | 0.89 | TLR7 (0.39) | TLR7IL6 | |
| SCHEMBL29475681 | 0.88 | BCHE (0.42) | TLR7IL6BCHEACHECACNA1F | |
| SCHEMBL29034532 | 0.87 | CHRM4 (0.44) | TLR7IL6ACHE | |
| SCHEMBL29475671 | 0.85 | TLR7 (0.43) | TLR7IL6BCHEACHE | |
| SCHEMBL29034540 | 0.85 | TLR7 (0.43) | TLR7IL6BCHEACHE | |
| SCHEMBL29034541 | 0.85 | TLR7 (0.43) | TLR7IL6BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113660957-A | Compositions, methods, and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2020168017-A1 | COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES | AMBRX, INC. (US) | 2020-08-20 | — | — | WO | disclosed |