Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.43 |
| ▸ | IL6 | P05231 | 9/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034540 | 1.00 | TLR7 (0.43) | TLR7IL6TLR8BCHEACHE | |
| SCHEMBL29034541 | 1.00 | TLR7 (0.43) | TLR7IL6TLR8BCHEACHE | |
| SCHEMBL26347307 | 0.88 | TLR7 (0.56) | TLR7IL6TLR8 | |
| SCHEMBL22359142 | 0.85 | TLR7 (0.40) | TLR7IL6BCHEACHE | |
| SCHEMBL28659945 | 0.85 | TLR7 (0.40) | TLR7IL6BCHEACHE | |
| SCHEMBL29034560 | 0.83 | CHRM4 (0.48) | TLR7IL6ACHE | |
| SCHEMBL29034555 | 0.83 | ACHE (0.47) | TLR7IL6ACHE | |
| SCHEMBL29475661 | 0.83 | ACHE (0.47) | TLR7IL6ACHE | |
| SCHEMBL22359282 | 0.83 | TLR7 (0.45) | TLR7IL6TLR8BCHEACHE | |
| SCHEMBL29034549 | 0.81 | TLR7 (0.54) | TLR7IL6TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4199968-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | Ambrx, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040596-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | AMBRX, INC. (US) | 2022-02-24 | — | — | WO | disclosed |