Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.39 |
| ▸ | IL6 | P05231 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475724 | 0.93 | TLR7 (0.39) | TLR7IL6 | |
| SCHEMBL29034537 | 0.93 | TLR7 (0.39) | TLR7IL6 | |
| SCHEMBL22359142 | 0.84 | TLR7 (0.40) | TLR7IL6 | |
| SCHEMBL28659945 | 0.84 | TLR7 (0.40) | TLR7IL6 | |
| SCHEMBL26347255 | 0.81 | TLR7 (0.53) | TLR7IL6 | |
| SCHEMBL29034532 | 0.81 | CHRM4 (0.44) | TLR7IL6 | |
| SCHEMBL29475681 | 0.78 | BCHE (0.42) | TLR7IL6 | |
| SCHEMBL26348220 | 0.78 | TLR7 (0.52) | TLR7IL6 | |
| SCHEMBL29034560 | 0.76 | CHRM4 (0.48) | TLR7IL6 | |
| SCHEMBL29034548 | 0.76 | CHRM4 (0.47) | TLR7IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020168017-A1 | COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES | AMBRX, INC. (US) | 2020-08-20 | — | — | WO | disclosed |