Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 6/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.45 |
| ▸ | IL6 | P05231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034548 | 0.95 | CHRM4 (0.47) | CHRM4ACHETLR7IL6 | |
| SCHEMBL29475661 | 0.93 | ACHE (0.47) | CHRM4ACHETLR7IL6 | |
| SCHEMBL29034555 | 0.93 | ACHE (0.47) | CHRM4ACHETLR7IL6 | |
| SCHEMBL22359264 | 0.91 | ACHE (0.46) | CHRM4ACHETLR7IL6 | |
| SCHEMBL29034532 | 0.90 | CHRM4 (0.44) | CHRM4ACHETLR7IL6 | |
| SCHEMBL22359282 | 0.89 | TLR7 (0.45) | CHRM4ACHETLR7IL6 | |
| SCHEMBL26347233 | 0.87 | TLR7 (0.63) | TLR7IL6 | |
| SCHEMBL26347245 | 0.83 | TLR7 (0.62) | TLR7IL6 | |
| SCHEMBL29475671 | 0.83 | TLR7 (0.43) | ACHETLR7IL6 | |
| SCHEMBL29034541 | 0.83 | TLR7 (0.43) | ACHETLR7IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |