SCHEMBL22360334

SCHEMBL22360334

COc1c(-c2ccccc2)cccc1-c1cccc(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 2/20 0.46
TUBB P07437 2/20 0.46
TUBA3C P0DPH7 2/20 0.46
TUBA1B P68363 2/20 0.46
TUBA4A P68366 2/20 0.46
TUBB4B P68371 2/20 0.46
TUBB3 Q13509 2/20 0.46
TUBB2A Q13885 2/20 0.46
TUBB8 Q3ZCM7 2/20 0.46
TUBA3E Q6PEY2 2/20 0.46
TUBA1A Q71U36 2/20 0.46
TUBA1C Q9BQE3 2/20 0.46
TUBB6 Q9BUF5 2/20 0.46
TUBB2B Q9BVA1 2/20 0.46
TUBB1 Q9H4B7 2/20 0.46
HPGD P15428 4/20 0.46
ALDH1A1 P00352 3/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12455941 0.87 PDE4B (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL13385087 0.86 PDE4B (0.48) HPGDALDH1A1SMN1; SMN2HSD17B10PDE4B
SCHEMBL27695762 0.85 HPGD (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL2922149 0.84 RAB9A (0.52) HPGDALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL23436763 0.82 ADORA2A (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL5459902 0.80 CNR2 (0.47) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL21808825 0.80 PDE4B (0.48) HPGDALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL30728866 0.80 TUBB4A (0.49) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL9876129 0.80 CNR2 (0.51) HPGDALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL757781 0.80 PDE4B (0.53) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11077433-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2021-08-03 US disclosed
US-20200261898-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200261898-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 TUBB4A 4691/4885TUBB 4682/4885TUBA3C 4830/4885
US-11077433-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 TUBB4A 4691/4885TUBB 4682/4885TUBA3C 4830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.