Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360382 | 0.86 | TP53 (0.52) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL22360371 | 0.86 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL22360380 | 0.86 | POLB (0.39) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL22360373 | 0.86 | PTK2 (0.45) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL22360420 | 0.85 | SMN1; SMN2 (0.55) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL22360492 | 0.83 | KDM4E (0.45) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL22360494 | 0.80 | L3MBTL1 (0.39) | RAB9ANPC1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL22360369 | 0.78 | POLB (0.54) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL22360419 | 0.78 | NOTUM (0.38) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL22360381 | 0.78 | NPC1 (0.40) | RAB9ANPC1SMN1; SMN2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020164403-A1 | 1,1-DICYANO-OXIME-ETHER COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2020-08-20 | — | — | WO | disclosed |