Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360375 | 0.87 | MAPT (0.51) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22360369 | 0.87 | POLB (0.54) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22360379 | 0.87 | POLB (0.49) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22360420 | 0.86 | SMN1; SMN2 (0.55) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22360380 | 0.85 | POLB (0.39) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22360487 | 0.84 | POLB (0.42) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22360493 | 0.84 | MAPT (0.46) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22360494 | 0.81 | L3MBTL1 (0.39) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22360419 | 0.79 | NOTUM (0.38) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22360418 | 0.78 | L3MBTL1 (0.36) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020164403-A1 | 1,1-DICYANO-OXIME-ETHER COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2020-08-20 | — | — | WO | disclosed |