Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360369 | 0.87 | POLB (0.54) | MAPTUSP2L3MBTL1POLBNPC1 | |
| SCHEMBL22360419 | 0.87 | NOTUM (0.38) | MAPTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL22360381 | 0.87 | NPC1 (0.40) | MAPTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL22360379 | 0.87 | POLB (0.49) | MAPTKMT2AL3MBTL1POLBHTT | |
| SCHEMBL22360420 | 0.86 | SMN1; SMN2 (0.55) | MAPTKMT2AMEN1L3MBTL1POLB | |
| SCHEMBL22360371 | 0.85 | NPC1 (0.48) | MAPTKMT2AL3MBTL1POLBGAA | |
| SCHEMBL22360487 | 0.84 | POLB (0.42) | MAPTKMT2AMEN1USP2POLB | |
| SCHEMBL22360494 | 0.84 | L3MBTL1 (0.39) | MAPTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL22360493 | 0.84 | MAPT (0.46) | MAPTKMT2AMEN1L3MBTL1POLB | |
| SCHEMBL22360489 | 0.83 | SMN1; SMN2 (0.45) | MAPTKMT2AMEN1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020164403-A1 | 1,1-DICYANO-OXIME-ETHER COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2020-08-20 | — | — | WO | disclosed |