Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293863 | 0.81 | GABRG2 (0.50) | SMN1; SMN2ALDH1A1SRD5A1GABRG2GABRB3 | |
| SCHEMBL2234469 | 0.81 | SRD5A1 (0.40) | SMN1; SMN2ALDH1A1GAASRD5A1GABRG2 | |
| SCHEMBL8223047 | 0.74 | MAPT (0.45) | SMN1; SMN2ALDH1A1GAASRD5A1MAPT | |
| SCHEMBL2238273 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL23192606 | 0.72 | SRD5A1 (0.50) | SMN1; SMN2ALDH1A1SRD5A1GABRG2GABRB3 | |
| SCHEMBL8224589 | 0.72 | PTPRA (0.40) | SMN1; SMN2ALDH1A1GAASRD5A1LMNA | |
| SCHEMBL10293868 | 0.71 | L3MBTL1 (0.39) | SMN1; SMN2ALDH1A1GAASRD5A1LMNA | |
| SCHEMBL10293869 | 0.71 | HSD17B3 (0.39) | SMN1; SMN2ALDH1A1GAASRD5A1LMNA | |
| SCHEMBL12849617 | 0.69 | SRD5A1 (0.34) | SMN1; SMN2ALDH1A1SRD5A1MAPTNPC1 | |
| SCHEMBL2236516 | 0.69 | SRD5A1 (0.43) | SMN1; SMN2SRD5A1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110213143-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-01 | — | — | US | disclosed |
| EP-2361910-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213143-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | TAF1, TAF5, TAF11 | SMN1; SMN2 4075/4885ALDH1A1 4182/4885GAA 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.