Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.51 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.51 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23337582 | 0.95 | CYP1A1 (0.51) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL12275866 | 0.89 | CYP1A1 (0.54) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL30704929 | 0.87 | CYP1A1 (0.53) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL20248867 | 0.86 | PTP4A3 (0.49) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL12275663 | 0.82 | CYP1A1 (0.49) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL2233095 | 0.82 | APP (0.47) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL19301020 | 0.79 | PTP4A3 (0.44) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL22107527 | 0.79 | PTP4A3 (0.44) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL12276144 | 0.79 | PTP4A3 (0.44) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL12275252 | 0.79 | PTP4A3 (0.44) | CYP1A1CYP1B1PTP4A3PTP4A2PTP4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361915-B1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | NIPPON KAYAKU KK (JP) | 2015-01-28 | — | — | EP | disclosed |
| EP-2361915-B1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | NIPPON KAYAKU KK (JP) | 2015-01-28 | — | — | EP | disclosed |
| US-8313671-B2 | Heterocyclic compound and use thereof | HIROSHIMA UNIVERSITY (JP) | 2012-11-20 | — | — | US | disclosed |
| US-8313671-B2 | Heterocyclic compound and use thereof | HIROSHIMA UNIVERSITY (JP) | 2012-11-20 | — | — | US | disclosed |
| US-8313671-B2 | Heterocyclic compound and use thereof | HIROSHIMA UNIVERSITY (JP) | 2012-11-20 | — | — | US | disclosed |
| EP-2361915-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | Hiroshima University (JP) | 2011-08-31 | — | — | EP | disclosed |
| US-20110204295-A1 | Novel Heterocyclic Compound And Use Thereof | HIROSHIMA UNIVERSITY (JP) | 2011-08-25 | — | — | US | disclosed |
| US-20110204295-A1 | Novel Heterocyclic Compound And Use Thereof | HIROSHIMA UNIVERSITY (JP) | 2011-08-25 | — | — | US | disclosed |
| US-20110204295-A1 | Novel Heterocyclic Compound And Use Thereof | HIROSHIMA UNIVERSITY (JP) | 2011-08-25 | — | — | US | disclosed |
| WO-2010058833-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | 国立大学法人広島大学 (JP) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110204295-A1 | Novel Heterocyclic Compound And Use Thereof | SCLY, C9, C1S | CYP1A1 119/4885CYP1B1 199/4885PTP4A3 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.