Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | STS | P08842 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14717579 | 0.88 | STS (0.43) | CA2CA1STSFFAR1CA9 | |
| SCHEMBL14717026 | 0.82 | STS (0.43) | CA2CA1STSCA9CA12 | |
| SCHEMBL2237810 | 0.82 | STS (0.57) | CA2CA1STSCA9CA12 | |
| SCHEMBL6136347 | 0.80 | FFAR1 (0.59) | CA2CA1FFAR1FFAR4 | |
| SCHEMBL14716778 | 0.78 | CA2 (0.64) | CA2CA1STSCA9CA12 | |
| SCHEMBL2237037 | 0.78 | CA2 (0.68) | CA2CA1STSCA9CA12 | |
| SCHEMBL2234949 | 0.78 | CA2 (0.68) | CA2CA1STSCA9CA12 | |
| SCHEMBL2239304 | 0.77 | CA2 (0.66) | CA2CA1STSCA9CA12 | |
| SCHEMBL2236615 | 0.77 | CA2 (0.66) | CA2CA1STSCA9CA12 | |
| SCHEMBL2235949 | 0.77 | CA2 (0.66) | CA2CA1STSCA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533775-A1 | CARBONIC ANHYDRASE INHIBITORS | Universita' Degli Studi di Firenze (IT) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011098610-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITA DEGLI STUDI DI FIRENZE (IT) | 2011-08-18 | — | — | WO | disclosed |