Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.66 |
| ▸ | CA9 | Q16790 | 12/20 | 0.66 |
| ▸ | CA1 | P00915 | 11/20 | 0.66 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | STS | P08842 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237810 | 0.86 | STS (0.57) | CA2CA9CA1CA12STS | |
| SCHEMBL2237247 | 0.84 | CA2 (0.65) | CA2CA9CA1CA12STS | |
| SCHEMBL2235949 | 0.84 | CA2 (0.66) | CA2CA9CA1CA12STS | |
| SCHEMBL2237446 | 0.84 | CA2 (0.57) | CA2CA9CA1CA12STS | |
| SCHEMBL2239304 | 0.84 | CA2 (0.66) | CA2CA9CA1CA12STS | |
| SCHEMBL14717706 | 0.82 | STS (0.73) | CA2CA9CA1CA12STS | |
| SCHEMBL2234949 | 0.82 | CA2 (0.68) | CA2CA9CA1CA12STS | |
| SCHEMBL2237037 | 0.82 | CA2 (0.68) | CA2CA9CA1CA12STS | |
| SCHEMBL9451347 | 0.81 | CA2 (1.00) | CA2CA9CA1CA12STS | |
| SCHEMBL2233585 | 0.81 | CA2 (0.69) | CA2CA9CA1CA12STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533775-A1 | CARBONIC ANHYDRASE INHIBITORS | Universita' Degli Studi di Firenze (IT) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011098610-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITA DEGLI STUDI DI FIRENZE (IT) | 2011-08-18 | — | — | WO | disclosed |