⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13584680 | 0.86 | — | — | |
| SCHEMBL4129946 | 0.81 | — | — | |
| SCHEMBL22380385 | 0.75 | CTSK (0.33) | — | |
| SCHEMBL15859416 | 0.73 | — | — | |
| SCHEMBL4693128 | 0.73 | MME (0.31) | — | |
| SCHEMBL3093430 | 0.71 | CYP2C19 (0.31) | — | |
| SCHEMBL19744800 | 0.68 | — | — | |
| SCHEMBL2746734 | 0.68 | LMNA (0.30) | — | |
| SCHEMBL26543372 | 0.68 | — | — | |
| SCHEMBL16653661 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3927698-A1 | AMIDE DERIVATIVES USEFUL IN THE TREATMENT OF HBV INFECTION OR HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-12-29 | — | — | EP | disclosed |
| US-20200268730-A1 | AMIDE DERIVATIVES USEFUL IN THE TREATMENT OF HBV INFECTION OR HBV-INDUCED DISEASES | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-27 | — | — | US | disclosed |