⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17503002 | 0.87 | — | — | |
| SCHEMBL13273709 | 0.71 | — | — | |
| SCHEMBL17502996 | 0.68 | — | — | |
| SCHEMBL2235100 | 0.65 | — | — | |
| SCHEMBL2223999 | 0.64 | — | — | |
| SCHEMBL22006118 | 0.64 | MAOA (0.41) | — | |
| SCHEMBL28238582 | 0.62 | — | — | |
| SCHEMBL12181529 | 0.60 | CYP3A4 (0.32) | — | |
| SCHEMBL8132863 | 0.60 | — | — | |
| Propene SCHEMBL278244 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791100-B2 | Aryl benzylamine compounds | NOVARTIS AG (CH) | 2014-07-29 | — | — | US | claimed |
| EP-2531487-B1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2014-06-18 | — | — | EP | claimed |
| EP-2531487-A1 | ARYL BENZYLAMINE COMPOUNDS | Novartis AG (CH) | 2012-12-12 | — | — | EP | claimed |
| WO-2011095452-A1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2011-08-11 | — | — | WO | claimed |
| US-20110190258-A1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2011-08-04 | — | — | US | claimed |
| EP-0520552-A1 | Derivatives of (hetero) aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them | PIERREL S.p.A. (IT) | 1992-12-30 | — | — | EP | claimed |
| WO-2023078909-A1 | CYCLIC ACETALS AND KETALS FOR THE LIGHT-INDUCED RELEASE OF ACTIVE ALDEHYDES AND KETONES | FIRMENICH SA (CH) | 2023-05-11 | — | — | WO | disclosed |
| US-8791100-B2 | Aryl benzylamine compounds | NOVARTIS AG (CH) | 2014-07-29 | — | — | US | disclosed |
| EP-2531487-B1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2014-06-18 | — | — | EP | disclosed |
| EP-2531487-A1 | ARYL BENZYLAMINE COMPOUNDS | Novartis AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| WO-2011095452-A1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2011-08-11 | — | — | WO | disclosed |
| US-20110190258-A1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2011-08-04 | — | — | US | disclosed |
| US-5470858-A | Anticholesterol agents | PIERREL SPA (IT) | 1995-11-28 | — | — | US | disclosed |
| EP-0571522-A1 | SYNTHESIS OF CYCLIC KETENE ACETALS. | EASTMAN KODAK CO (US) | 1993-12-01 | — | — | EP | disclosed |
| EP-0520552-A1 | Derivatives of (hetero) aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them | PIERREL S.p.A. (IT) | 1992-12-30 | — | — | EP | disclosed |
| WO-1992014722-A1 | SYNTHESIS OF CYCLIC KETENE ACETALS | EASTMAN KODAK COMPANY (US) | 1992-09-03 | — | — | WO | disclosed |
| US-4466903-A | Unsaturated 1,3-dioxolane stabilized with aliphatic aldehyde hydrazone | PPG INDUSTRIES, INC. (US) | 1984-08-21 | — | — | US | disclosed |
| US-4418231-A | ACID ACCEPTING 2-ALKYLIDENE-1,3-DIOXOLANES IN TRICHLOROETHYLENE AND/OR METHYLCHLOROFORM | PPG INDUSTRIES, INC. (US) | 1983-11-29 | — | — | US | disclosed |