⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2027735 | 0.72 | TSHR (0.36) | — | |
| SCHEMBL18231554 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL27676807 | 0.69 | — | — | |
| SCHEMBL24385392 | 0.67 | — | — | |
| SCHEMBL2361853 | 0.67 | — | — | |
| SCHEMBL6299237 | 0.66 | — | — | |
| SCHEMBL2236437 | 0.65 | — | — | |
| SCHEMBL9620051 | 0.65 | — | — | |
| SCHEMBL8593736 | 0.64 | — | — | |
| SCHEMBL29368225 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102741227-B | Aryl benzylamine compounds | NOVARTIS AG | 2014-07-30 | — | — | CN | claimed |
| US-8791100-B2 | Aryl benzylamine compounds | NOVARTIS AG (CH) | 2014-07-29 | — | — | US | claimed |
| EP-2531487-B1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2014-06-18 | — | — | EP | claimed |
| EP-2531487-A1 | ARYL BENZYLAMINE COMPOUNDS | Novartis AG (CH) | 2012-12-12 | — | — | EP | claimed |
| CN-102741227-A | Aryl benzylamine compounds | NOVARTIS AG | 2012-10-17 | — | — | CN | claimed |
| WO-2011095452-A1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2011-08-11 | — | — | WO | claimed |
| US-20110190258-A1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2011-08-04 | — | — | US | claimed |
| JP-10139712-A | — | — | None | — | — | JP | disclosed |
| CN-102741227-B | Aryl benzylamine compounds | NOVARTIS AG | 2014-07-30 | — | — | CN | disclosed |
| US-8791100-B2 | Aryl benzylamine compounds | NOVARTIS AG (CH) | 2014-07-29 | — | — | US | disclosed |
| EP-2531487-B1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2014-06-18 | — | — | EP | disclosed |
| EP-2531487-A1 | ARYL BENZYLAMINE COMPOUNDS | Novartis AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| CN-102741227-A | Aryl benzylamine compounds | NOVARTIS AG | 2012-10-17 | — | — | CN | disclosed |
| US-7671231-B2 | L-allysine acetal prepared by contacting a 2-butene acetal with a hydroformylation catalyst and synthesis gas to prepare aldehyde mixture; contacting with an enantioselective hydrolase in the presence of water and hydrocyanic acid/ammonia; separation from branched derivatives | LLOYD MICHAEL C | 2010-03-02 | — | — | US | disclosed |
| WO-2007084545-A1 | PROCESS FOR MAKING AMINO ACIDS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20070166806-A1 | Process for making amino acids | LLOYD MICHAEL C | 2007-07-19 | — | — | US | disclosed |
| US-20070166806-A1 | Process for making amino acids | LLOYD MICHAEL C | 2007-07-19 | — | — | US | disclosed |
| CN-1133643-C | Lactone derivatives of 17-beta-carboxy, carbothio and amide androstane derivatives | — | 2004-01-07 | — | — | CN | disclosed |
| CN-1209135-A | Lactone derivatives of 17-beta-carboxy, carbothio and amide androstane derivatives | GLAXO GROUP LTD (GB) | 1999-02-24 | — | — | CN | disclosed |
| JP-H10139712-A | PRODUCTION OF NAPHTHYLBUTANONE | ARCHIMICA SPA | 1998-05-26 | — | — | JP | disclosed |