⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29757278 | 0.65 | KDM4E (0.36) | — | |
| SCHEMBL6118600 | 0.62 | — | — | |
| SCHEMBL28658792 | 0.62 | CA2 (0.42) | — | |
| SCHEMBL1327389 | 0.59 | CA12 (0.33) | — | |
| SCHEMBL28664612 | 0.58 | CA12 (0.46) | — | |
| SCHEMBL3205912 | 0.58 | — | — | |
| SCHEMBL28650137 | 0.58 | CA2 (0.42) | — | |
| SCHEMBL28947348 | 0.58 | CDC25B (0.41) | — | |
| SCHEMBL28961176 | 0.55 | — | — | |
| SCHEMBL8797345 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130130263-A1 | GAMETES SEPARATION METHODS, COMPOSITIONS AND USES THEREOF | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) | 2013-05-23 | — | — | US | claimed |
| EP-2539434-A1 | GAMETES SEPARATION METHODS, COMPOSITIONS AND USES THEREOF | Assistance Publique - Hôpitaux de Paris (FR) | 2013-01-02 | — | — | EP | claimed |
| WO-2011104336-A1 | GAMETES SEPARATION METHODS, COMPOSITIONS AND USES THEREOF | ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS (FR) | 2011-09-01 | — | — | WO | claimed |
| EP-2361967-A1 | Gametes separation methods, compositions and uses thereof | Assistance Publique - Hôpitaux de Paris (FR) | 2011-08-31 | — | — | EP | claimed |
| US-20150011513-A1 | ALKYNE-, AZIDE- AND TRIAZOLE-CONTAINING FLAVONOIDS AS MODULATORS FOR MULTIDRUG RESISTANCE IN CANCERS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2015-01-08 | — | — | US | disclosed |
| US-8916549-B2 | Thienooxazepine derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-12-23 | — | — | US | disclosed |
| US-8916549-B2 | Thienooxazepine derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-12-23 | — | — | US | disclosed |
| EP-2463290-B1 | THIENOOXAZEPINE DERIVATIVE | TAKEDA PHARMACEUTICAL (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20130130263-A1 | GAMETES SEPARATION METHODS, COMPOSITIONS AND USES THEREOF | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) | 2013-05-23 | — | — | US | disclosed |
| EP-2539434-A1 | GAMETES SEPARATION METHODS, COMPOSITIONS AND USES THEREOF | Assistance Publique - Hôpitaux de Paris (FR) | 2013-01-02 | — | — | EP | disclosed |
| US-20120196848-A1 | THIENOOXAZEPINE DERIVATIVE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-02 | — | — | US | disclosed |
| EP-2463290-A1 | THIENOOXAZEPINE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011104336-A1 | GAMETES SEPARATION METHODS, COMPOSITIONS AND USES THEREOF | ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS (FR) | 2011-09-01 | — | — | WO | disclosed |
| EP-2361967-A1 | Gametes separation methods, compositions and uses thereof | Assistance Publique - Hôpitaux de Paris (FR) | 2011-08-31 | — | — | EP | disclosed |