⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236497 | 0.58 | — | — | |
| SCHEMBL18873468 | 0.47 | — | — | |
| SCHEMBL21952429 | 0.41 | CES1 (0.67) | — | |
| SCHEMBL5086992 | 0.35 | — | — | |
| Benzoquinone SCHEMBL3208089 | 0.29 | — | — | |
| Benzoquinone SCHEMBL5308519 | 0.29 | ALDH1A1 (1.00) | — | |
| Benzoquinone SCHEMBL937988 | 0.28 | — | — | |
| SCHEMBL10066089 | 0.26 | — | — | |
| SCHEMBL9635785 | 0.26 | — | — | |
| SCHEMBL3000562 | 0.24 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113823749-A | Organic electroluminescent device, display panel and display device | 京东方科技集团股份有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-115627027-A | Encapsulated stabilizer composition | 塞特工业公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-113823749-A | Organic electroluminescent device, display panel and display device | 京东方科技集团股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| US-20120232025-A1 | SAFENER DRUG COMBINATIONS FOR USE WITH NMDA ANTAGONIST DRUGS | OLNEY JOHN W (US) | 2012-09-13 | — | — | US | disclosed |
| US-20100160371-A1 | INHIBITION OF P38 KINASE ACTIVITY BY ARYL UREAS | RANGES GERALD | 2010-06-24 | — | — | US | disclosed |
| WO-2010019930-A1 | UREA DERIVATIVES AS INHIBITORS OF MAP KINASES | LOCUS PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20100041642-A1 | UREA INHIBITORS OF MAP KINASES | LOCUS PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| EP-1019040-B1 | ARYL UREAS FOR THE TREATMENT OF INFLAMMATORY OR IMMUNOMODULATORY DISEASES | BAYER AG (US) | 2004-09-29 | — | — | EP | disclosed |
| US-20020103253-A1 | Inhibition of p38 kinase activity by aryl ureas | BAYER CORPORATION (US) | 2002-08-01 | — | — | US | disclosed |
| US-6344476-B1 | Inhibition of p38 kinase activity by aryl ureas | BAYER CORPORATION | 2002-02-05 | — | — | US | disclosed |
| EP-1019040-A4 | INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS | BAYER AG (US) | 2000-10-04 | — | — | EP | disclosed |
| EP-1019040-A1 | INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS | Bayer Corporation (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998052558-A1 | INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS | BAYER CORPORATION (US) | 1998-11-26 | — | — | WO | disclosed |
| US-4760063-A | Thienooxazinones, processes for their preparation, and their use as growth promoters | BAYER AKTIENGSELLSCHAFT (DE) | 1988-07-26 | — | — | US | disclosed |
| US-4234581-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4159377-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4054656-A | ASTHMA, HAY FEVER, FOODS | MEAD JOHNSON & COMPANY (US) | 1977-10-18 | — | — | US | disclosed |