Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19668681 | 0.83 | CYP3A4 (0.59) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL29363322 | 0.83 | CYP3A4 (0.59) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL15093706 | 0.80 | CYP3A4 (0.71) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL31071488 | 0.80 | CYP3A4 (0.71) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL210120 | 0.79 | CYP3A4 (0.61) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL14035283 | 0.78 | CYP3A4 (0.58) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL20818634 | 0.78 | CYP3A4 (0.58) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL30476445 | 0.78 | CYP3A4 (0.58) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL8473516 | 0.74 | CYP3A4 (0.53) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL8473520 | 0.74 | CYP3A4 (0.53) | CYP3A4CYP3A5GPR119PLA2G7MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698782-A1 | CARBAMATE COMPOUNDS FOR USE IN THERAPY | Lundbeck La Jolla Research Center, Inc. (US) | 2020-08-26 | — | — | EP | disclosed |