Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365404 | 0.92 | FFAR1 (0.56) | FFAR1SCN3A | |
| SCHEMBL22365327 | 0.91 | FFAR1 (0.64) | FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL22365291 | 0.86 | FFAR1 (0.58) | FFAR1 | |
| SCHEMBL22365412 | 0.83 | FFAR1 (0.61) | FFAR1 | |
| SCHEMBL22365374 | 0.82 | FFAR1 (0.61) | FFAR1SCN3A | |
| SCHEMBL22365351 | 0.81 | FFAR1 (0.56) | FFAR1HTR2AHTR2CHTR2BSCN3A | |
| SCHEMBL8802456 | 0.81 | TAAR1 (0.61) | — | |
| SCHEMBL22365427 | 0.80 | FFAR1 (0.62) | FFAR1HTR2AHTR2CHTR2BSCN3A | |
| SCHEMBL22365266 | 0.80 | FFAR1 (0.58) | FFAR1SCN3A | |
| SCHEMBL22365225 | 0.80 | FFAR1 (0.58) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102198-B1 | ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2020-08-26 | — | — | EP | disclosed |