Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365322 | 0.90 | FFAR1 (0.64) | FFAR1FFAR4MMEACECPA1 | |
| SCHEMBL22365404 | 0.86 | FFAR1 (0.56) | FFAR1SCN3A | |
| SCHEMBL22365350 | 0.82 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL22365237 | 0.82 | ACACA (0.50) | — | |
| SCHEMBL22365454 | 0.81 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL22365447 | 0.81 | GPR88 (0.43) | FFAR1 | |
| SCHEMBL22365453 | 0.80 | FFAR1 (0.60) | FFAR1ADAM17MMEACECPA1 | |
| SCHEMBL22365347 | 0.80 | FFAR1 (0.58) | FFAR1SCN3A | |
| SCHEMBL22365407 | 0.80 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL17000407 | 0.80 | FFAR1 (0.84) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102198-B1 | ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2020-08-26 | — | — | EP | disclosed |