Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365427 | 0.90 | FFAR1 (0.62) | FFAR1HTR2AHTR2CHTR2BSCN3A | |
| SCHEMBL22365347 | 0.81 | FFAR1 (0.58) | FFAR1HTR2AHTR2CHTR2BSCN3A | |
| SCHEMBL22365327 | 0.80 | FFAR1 (0.64) | FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL63100 | 0.80 | HDAC1 (0.61) | CHRM2CHRM1CHRM3HDAC1HDAC6 | |
| SCHEMBL3929685 | 0.78 | KDM5A (0.48) | FFAR1GAA | |
| SCHEMBL8088837 | 0.78 | FFAR1 (0.55) | FFAR1HTR2AHTR2CHTR2BSCN3A | |
| SCHEMBL8088838 | 0.78 | FFAR1 (0.55) | FFAR1HTR2AHTR2CHTR2BSCN3A | |
| SCHEMBL17000376 | 0.77 | FFAR1 (0.84) | FFAR1 | |
| SCHEMBL8088922 | 0.75 | MTNR1A (0.49) | HDAC1HDAC6GLA | |
| SCHEMBL8088924 | 0.75 | MTNR1A (0.49) | HDAC1HDAC6GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102198-B1 | ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2020-08-26 | — | — | EP | disclosed |