Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 12/20 | 0.73 |
| ▸ | CA2 | P00918 | 7/20 | 0.59 |
| ▸ | CA9 | Q16790 | 7/20 | 0.59 |
| ▸ | CA1 | P00915 | 6/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239304 | 0.85 | CA2 (0.66) | STSCA2CA9CA1CA12 | |
| SCHEMBL2237247 | 0.85 | CA2 (0.65) | STSCA2CA9CA1CA12 | |
| SCHEMBL2237810 | 0.83 | STS (0.57) | STSCA2CA9CA1CA12 | |
| SCHEMBL5174398 | 0.82 | NOS3 (0.50) | STSNPSR1 | |
| SCHEMBL2235949 | 0.82 | CA2 (0.66) | STSCA2CA9CA1CA12 | |
| SCHEMBL2236615 | 0.82 | CA2 (0.66) | STSCA2CA9CA1CA12 | |
| SCHEMBL2237446 | 0.82 | CA2 (0.57) | STSCA2CA9CA1CA12 | |
| SCHEMBL6799997 | 0.80 | STS (0.62) | STSCA2CA9CA1CA12 | |
| SCHEMBL2234949 | 0.79 | CA2 (0.68) | STSCA2CA9CA1CA12 | |
| SCHEMBL2237037 | 0.79 | CA2 (0.68) | STSCA2CA9CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITETET I OSLO (NO) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | CA9, CA2, CA4 | STS 92/4885CA2 2/4885CA9 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.