Sugi Predict

Sugi Predict / Compounds / SCHEMBL22366271

SCHEMBL22366271

SCHEMBL22366271

CCC(CF)CCCCCOC

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.33
▸ CYP3A4 P08684 3/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28996401 0.87 ALDH1A1 (0.38) ALDH1A1CYP3A4L3MBTL1TDP1LMNA
SCHEMBL27254682 0.85 ALDH1A1 (0.37) ALDH1A1CYP3A4L3MBTL1TDP1LMNA
SCHEMBL27254674 0.83 ALDH1A1 (0.35) ALDH1A1CYP3A4L3MBTL1TDP1LMNA
SCHEMBL20036173 0.78 ALDH1A1 (0.41) ALDH1A1CYP3A4TDP1LMNATSHR
SCHEMBL22339341 0.78 LMNA (0.52) ALDH1A1CYP3A4L3MBTL1TDP1LMNA
SCHEMBL25493270 0.78 LMNA (0.52) ALDH1A1CYP3A4L3MBTL1TDP1LMNA
SCHEMBL18484873 0.78 LMNA (0.52) ALDH1A1CYP3A4L3MBTL1TDP1LMNA
SCHEMBL11589419 0.77 CYP3A4 (0.40) ALDH1A1CYP3A4L3MBTL1TDP1TSHR
SCHEMBL19333630 0.76 LMNA (0.50) LMNATSHR
SCHEMBL11891936 0.74 ALDH1A1 (0.38) ALDH1A1CYP3A4TDP1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3434668-B1 INDOLO-SUBSTITUTED-PIPERIDINE COMPOUNDS AS ESTROGEN RECEPTOR DEGRADING AGENT LUOXIN PHARMACEUTICAL SHANGHAI CO LTD (CN) 2020-08-26 — — EP disclosed