Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678849 | 1.00 | ABHD6 (0.58) | ABHD6ESR2SCN9AMAPK1NR1H2 | |
| SCHEMBL22366351 | 0.90 | ABHD6 (0.57) | ABHD6ESR2SCN9AMAPK1NR1H2 | |
| SCHEMBL30429034 | 0.90 | ABHD6 (0.57) | ABHD6ESR2SCN9AMAPK1NR1H2 | |
| SCHEMBL22366375 | 0.90 | ABHD6 (0.57) | ABHD6ESR2SCN9AMAPK1NR1H2 | |
| SCHEMBL30429074 | 0.90 | ABHD6 (0.57) | ABHD6ESR2SCN9AMAPK1NR1H2 | |
| SCHEMBL20983850 | 0.90 | ABHD6 (0.71) | ABHD6ESR2SCN9AMAPK1NR1H2 | |
| SCHEMBL5450422 | 0.90 | ABHD6 (0.56) | ABHD6ESR2SCN9AMAPK1NR1H2 | |
| SCHEMBL8184661 | 0.87 | ABHD6 (0.53) | ABHD6ESR2SCN9AMAPK1NR1H2 | |
| SCHEMBL5100971 | 0.86 | HRH3 (0.62) | ABHD6UCHL1HRH3MAPTS1PR5 | |
| SCHEMBL25386158 | 0.86 | ABHD6 (0.52) | ABHD6ESR2SCN9AMAPK1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3700911-B1 | NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2023-09-06 | — | — | EP | disclosed |
| EP-3700911-A1 | NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier SAS (FR) | 2020-09-02 | — | — | EP | disclosed |